Allied health – 3007. The biomarker of sublingual immune therapy

نویسندگان

  • Masafumi Sakashita
  • Yoshimasa Imoto
  • Yoko Osawa
  • Noboru Takahashi
  • Seita Kubo
  • Hideyuki Yamamoto
  • Takechiyo Yamada
  • Shigeharu Fujieda
چکیده

Background Allergic rhinitis (AR) is recognized as a major health problem worldwide. Allergen-specific immunotherapy (SIT) is the only available treatment that can alter the natural course of allergic disease. Recent findings in experimental models of allergic rhinitis suggest that complement 3a and 5a regulate the development of maladaptive Th2 and Th17 immunity. We investigated the changes of C3a, C5a, IL-17a in the serum of patients treated by Sublingual immune therapy (SLIT).

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عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2013